Regulation of proximal tubule vacuolar H+-ATPase by PKA and AMP-activated protein kinase
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منابع مشابه
Regulation of proximal tubule vacuolar H(+)-ATPase by PKA and AMP-activated protein kinase.
The vacuolar H(+)-ATPase (V-ATPase) mediates ATP-driven H(+) transport across membranes. This pump is present at the apical membrane of kidney proximal tubule cells and intercalated cells. Defects in the V-ATPase and in proximal tubule function can cause renal tubular acidosis. We examined the role of protein kinase A (PKA) and AMP-activated protein kinase (AMPK) in the regulation of the V-ATPa...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2014
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00362.2013